Comparative Studies on Distortion Product Otoacoustic Emissions and Compound Action Potential in Cisplatin Treated Guinea Pigs.
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چکیده
منابع مشابه
Distortion product otoacoustic emissions in tinnitus patients.
Tinnitus is a symptom that affects a great number of patients. Its diagnosis, treatment, and follow-up are difficult, owing to its subjectivity. The authors propose the use of distortion product otoacoustic emissions (DPOAEs) in tinnitus evaluation. They studied three groups: controls, having no complaint of tinnitus and normal hearing; group 1, presenting tinnitus and normal audiometry; and gr...
متن کاملDistortion-product otoacoustic emissions and auditory brainstem responses sensitivity assessment in cisplatin-induced ototoxicity in rats.
UNLABELLED Cisplatin (cis-diamminedicloroplatinum) is an antineoplastic drug used in the treatment of a variety of cancers, especially head-and-neck cancer. Its ototoxicity, however, has been noted as a common side-effect which limits its use and causes significant morbidity. AIM to assess distortion-product otoacoustic emissions (DPOAE) and brainstem evoked response audiometry (BERA) sensiti...
متن کاملEffects of cigarette smoking on distortion product otoacoustic emissions.
This study measured distortion product otoacoustic emissions (DPOAEs) and DPOAE input/output (I/O) curves to assess the effects of smoking on cochlear function. Twenty-four healthy adults, 12 smokers and 12 nonsmokers in the 20-30 years age range were selected based on self-reported histories of five to eight years of smoking or no smoking, respectively. All subjects received tympanometric scre...
متن کاملFine Structure in Distortion Product Otoacoustic Emissions and Auditory Perception
4 The influence of the second source of distortion product otoacoustic emissions (DPOAE) on DPOAE input/output functions 41 INTRODUCTION 42 I. EXPERIMENTAL METHODS 45 A. Subjects 45 B. Instrumentation and signal processing 45 C. Calibration 46 D. DPOAE measurements 46 II. DATA ANALYSIS 47 A. Separation of DPOAE components via time windowing 47 B. DPOAE threshold according to Boege and Janssen 5...
متن کاملCisplatin ototoxicity, increased DPOAE amplitudes, and magnesium deficiency. Distortion product otoacoustic emissions.
Outer hair cell (OHC) metabolism is blocked by cisplatin. Concurrent changes in the renal handling of magnesium occur because of the damage cisplatin causes to the renal proximal tubule cells within the thick ascending loop of Henle. Although there is no evidence of cisplatin within the OHCs, there are significant levels of intracellular calcium, the antagonist to magnesium at the cell membrane...
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ژورنال
عنوان ژورنال: AUDIOLOGY JAPAN
سال: 1997
ISSN: 1883-7301,0303-8106
DOI: 10.4295/audiology.40.719